List of Palms & Soles Rashes

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palms soles rashIn USMLE exams you will probably come  across ~3-7 questions on palms and soles rash. This list of diseases causing this rash is very high yield to memorize for USMLE.

Here is the list:

  • Meningococcemia
  • Keratoderma blenorrhagica (Reiter’s syndrome)
  • Typhus
  • Acral lentiginous melanoma
  • Hand, Foot, and Mouth Disease
  • Mercury poisoning in children
  • Bacterial endocarditis
  • Tylosis
  • Rocky Mountain Spotted Fever
  • Graft Versus Host Disease rash.
  • Kawasaki, Measles, or Toxic Shock Syndrome
  • Steven Johnson syndrome
  • Secondary and Congenital Syphilis with it’s characteristic Copper colored rash.
  • Michael Beckham

    I believe Typhus is a rash that spares the palms and soles, rather than being on the palms and soles.

    • Anonymous

      Yes, classically described as sparing the palms and soles, but exceptions are documented to have occured.

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