Owl’s eye appearance as shown on histopathology

Owl’s eye appearance is a pattern in radiology and histopathology. It is seen in:


  • Herpes Viruses Family infection as inclusion bodies, which are more commonly associated with cytomegalovirus.
  • Hodgkin’s lymphoma as Reed-Sternberg cells
  • Giardia lamblia trophozoites on microscopy.
  • Anitschkow cell of Aschoff bodies in rheumatic heart disease on transverse sections


  • CT scan of Cerebral hypoxia patients in Lentiform nucleus of the basal ganglia.